Monday, May 22, 2006

Last Final EVER....

My last final is tomorrow at 1:00. I have a paper due at 8:00, too. Busy busy busy.

Final countdown.

Ba ba ba dum, ba da da da dum. Ba da da dum, ba da da da da da daaaa da da daaaa da da daaa-da-daaa-da-daa da deeeeeeeeeeeeeeeeeeeeee de de de de de dooo.... final countdown.

Go HHS marching band.

I need sleep.

Tuesday, May 16, 2006

Hercules Boyum

I savor the Herculean labor of protein-ligand and protein-protein thermodynamics and kinetics. Aaaahh... (More later.)

Monday, May 15, 2006

The Advantages of Being Lutheran

Well, I found out today that I got one med school scholarship I was hoping for. The ELCA gives out four $5,000 scholarships each year to entering med students, and I got one of them. That helps out a bunch.

What might have been more valuable than the stipend was the process, because it required me to put together my resume, which in turn required me to put together a plan for my life. Which is kind of scary, when you try to think about what you'll be able (and won't) to change in your lifetime -- especially in a system as screwed up as the American health care system.

I tried to label this Problem #1, but I found that I had no #2. Here it is, black and white, agree or disagree.

Restricted treatment for the underclasses. There. I said it. Marxists cheer, capitalists cringe.

Medicine, as practiced today, individualizes social problems to a set of symptoms and prescribes treatments for those symptoms (Link and Phelan, 1995). For example, if I have AIDS (I don't, but what if...), how did I get AIDS? If I contracted the disease from sex, chances are I didn't use protection. In St. Louis (5th nationally for AIDS diagnoses), condoms cost on average $1-2 more per package in black neighborhoods than in white neighborhoods (Ross et al 2005). In Kalamazoo, MI, the two local hospitals were beginning to see children coming in with lead poisoning. Why? Because in low-income housing, predominantly peopled with the community's African-American population, the paint hadn't been replaced in decades - thus it still contained lead (which tastes sweet, and children love it). Everyone knows that bad foods lead to obesity, which is a major cause of diabetes. In Northern Ontario, the Sandy Lake community of Oji-Cree natives holds the population with the world's third largest percentage of diabetics. Part of the problem is genetic, but part of the problem is that fresh fruits and vegetables are virtually unheard of there. One woman said that when available they can cost up to $9/lb. Thus, they are limited to eating the processed foods that are easy and cheap to ship - Klik (Spam in the States), Kraft dinner (mac and cheese), and Ramen noodles. These are just three examples that I know of from personal experience. Many other national studies have been done that have found socioeconomic status and race to be top predictors of disease. Without proper education, housing, drinking water, diet, etc. etc. ad infinitum how can we expect to curb the health care disparities in America and the rest of the world?

How about research? Academic science pays no mind to economics, right? Wrong. Here's how science really works: the government or a private industry gives you money to conduct research. Somtimes you work directly for a corporation, e.g. the pharmaceutical industry. If you do "good enough" research, then you (or the company you work for) can apply for a patent to restrict access to a result. I should say that when you're able to get a patent, then you have arrived at "good" research in America. Usually when a patent happens in academia the scientist forms a "spin-off" company that functions independently from the college or university. These spin-off companies sell technology developed using the scientific "intellectual property." For example, Dr. Robert Gallo, who was here on campus not too long ago, pinpointed the HIV-1 virus as the causative agent of AIDS. From there was founded the Institute for Human Virology, Maryland BioTherapeutics, etc etc (Balt. Bus. J. 2005). These companies put forward the HIV-1 antibodies test as well as work on an AIDS vaccine (exciting!) and cancer therapies (20% of all human cancers are caused by retroviruses like HIV-1). Interestingly, quoting the Baltimore Business Journal, Gallo has been "long criticized by state lawmakers for not commercializing the research done in his institute" (ibid).

What's the result? The only research (medical or otherwise) that gets done (i.e. funded) is the research that benefits those with enough political power to influence state and national politics in post-industrialized, capitalist, powerful countries (the bourgeoisie if you're a Marx fan). Few labs in the world study trypanosomes, the microbes that cause African sleeping sickness, Mycobacterium tuberculosis (self-explanatory, or Leishmania, the pathogen causing leishmaniasis. Why? It's not because they aren't important. One-third of the world's population -- 2 billion people! -- are infected with the tuberculosis bug. Two million die each year from it. Up to 10% of those infected (200 million at present) will have the active disease in their lifetime. Why isn't more being done? The explanation is fairly simple: the nations that have enough resources to fund a robust public research sector (USA, UK, Western Europe) choose to fund research into other diseases that affect us more "today." As a result, the most prolific mycobacteria research lab in the world is in India, part of what some would consider to be the "third world."

So what needs to happen in order to make a first step toward equality in scientific coverage, to make sure that diseases that really affect people are researched? We need to do two things. First, we need to form an international body to fund research. Think international NIH. Second, we need to do away with the concept of "intellectual property" as it relates to scientific discoveries. This will hurt the current system of capitalist science that is currently being practiced, but it will repay that lost in the dividends of saved lives.

OK. There's my diatribe for tonight. Now I have to watch some Futurama.

:)

--Refs, in case you're interested:
Link BG, Phelan J. 1995. J. Health Soc. Beh. 35:80-94.
Ross W, et al. St. Louis Post-Dispatch, Jan 2005.
Terry RJ. Baltimore Business Journal, 4 Feb 2005.

Saturday, May 06, 2006

Just Keep Swimming

Corny Finding Nemo quotes aside, things have seemed to devolve of late.

(1) Got my financial aid "award" from med school. I think they use "award" in the same sense that one says a puppy may leave a "present" for you on your carpet. Our expected family contribution doubled somehow from last year. Might be a mistake, that's what I'm hoping for. Otherwise, I don't know how I'm going to pay $25,000 out of pocket every year, in addition to accumulating ~$25,000 of loans every year. And if I can't pay...... then..... what? This line of thought goes downhill relatively quickly.

(2) Whenever someone tells me, "You're almost done, eh?" I shudder.

School sucks. I've spent the last few days almost entirely working on lab projects or my symposium presentation. I worked from 6:30am Thursday morning to 1:30am Friday morning on my presentation, which I gave Friday to a huge crowd of 5. (One was my advisor. Another one was the prof who had to stay to give the introductions of the speakers.) We have one out that would keep our lab project afloat, otherwise the past few weeks of work have been in vain. Frustrating.

On top of that, I have two papers due Monday that I have had no time to work on all week. One's a 10 page term paper, the other's a rough draft of a lab report that's going to be around 15-20 pages all told. The parents & grandparents are down this weekend, and though it's good to see them it sucks having to be distracted from a good weekend with them by the papers. Thursday my final research proposal (full length, NIH-style) is due, with a complete outline of experiments that I "plan" to "perform." I will not actually ever get the chance to do the experiments, of course. We just have to pretend that we know what the hell is going on with advanced methods in biochemistry.

So yeah, whenever someone tells me, "So, you're almost done, eh?" I shudder.


Well, I've returned to blathering on about my problems. It's hard to abstain from it. On the other hand, the glass remains half full. I am in to med school, which a lot of people would die for. I am in to Wash U, which makes me pretty darn proud. I am getting paid $3500 this summer to do two things I love: research and being in the clinic. Dad's doing really well. He gets his last antibiotic IV next week, gets the IV line out, and then goes for joint replacement around the end of May. Then, on June 3 we all go to Movin' Out, Billy Joel's musical, in Madison.

I guess that's life, eh? Taking the good with the bad, bad with the good. I'm really uncomfortable with the problems I don't have control over (i.e. money). The papers have always worked themselves out before. I guess there's no reason to assume they won't this time.

"If you take life too seriously for too long, it'll get you." -Erik Estrada