Saturday, March 03, 2007

Will and Grace

So I just finished Season 3 of "Will & Grace." And of course, like most good shows, it's not like the season ended in a cliffhanger. So, I was very much looking forward to be able to skip right to the first episode of season 4, which I quickly found out was in Italian, courtesy of Mininova.org.

Now I'm not watching the 4th season of Will & Grace, so I guess I'll write some in my blog.

Which brings up the obvious question: what the hell is new in my life?

This calls for a list.

#1. I've fallen hard for Will & Grace. Belly laughs at every turn. "The only reason we hate gay people is because it's in right now. We hate gays, we hate evolution... it's like a new Age of Enlightenment."

#2. Belly... ew. I'm clocking in at an all-time high, 167 lbs. I'm going to the gym. They must make a machine for this. (Can't wait for the pill...)

#3. Becoming Martha Stewart. I think I'm getting good at this. I cooked dinner for a couple friends a few weeks ago (it wasn't even Easy Mac), and now I'm going to have a genetics homework marathon at my apartment. It may not sound sexy, but let me tell you...

#4. Concerts. It's wonderful to live in a city that is actually on "the tour schedule." Bob Saget (not to be confused with Danny Tanner) at the beginning of February - that was a fantastic night. Upcoming are Billy Joel in April and Damien Rice in May.

#5. Studying. Yup, some of that, too. Genetics, immunology, histology, physiology, and microbiology.

#6. World of Warcraft, next in my search for video games that I can't beat in a week. Let's just say that it's been much longer than that, and the $15/month I pay them is used to add even more onto it. Good game, if you find you have tons of free time (which I do, of course, being in medical school).

#7. Taking an elective on Health & Human Rights, which you'd think would go hand in hand, until you learn about the "doctors" at Abu Graihb (probably misspelled) and Guantanamo Bay.

#8. Research. Putting together a research proposal for this summer, so I can make some $$ to afford to stay in school. That would be good.

... OK, that makes my life sound boring. It's actually not. Honest.

Saturday, December 02, 2006

The monthly blog.

Well, we're out of power again in St. Louis. This is really starting to suck. Twice in the past 5 months my power has gone out for more than 24 hours. Last time was 71 hours. Honestly. I was counting down the time until I could say, "Hey, my power's been out for 3 days." Then, one hour before the big anniversary, I felt a cool blast of air conditioning that felt like diving into the lake after a sauna.

I swear that the electric company has a sinister plan behind these outages. The outage in July happened to fall on one of the hottest weeks in the year. Most days it was 95+ degrees during the outage. Suddenly now, the power goes out and the weather drops from the 50's and 60's to the 10's and 20's. It's like Ameren is saying, "See how much your life sucks without our product?" Meanwhile, I shiver and take a bath by splashing water on my hair and face, and by that point say, "OK, that's enough. The deodorant will take care of the rest."

The inconveniences don't stop there. I've been put in the unfortunate position of having to do laundry, read, and study today as opposed to what I truly should be doing -- playing World of Warcraft, watching Futurama, and going to our class Christmas party (which of course means getting schnockered, stumbling home, and falling asleep on the couch in my Christmas sweater). Of course, going to the Christmas party requires shaving and showering, the costs of which outweigh the benefit of going to it -- for a few reasons. (1) I have never shaved with a non-electric razor, and I don't want to show up to the party with tissue on my face. (2) Shaving with an electric razor in public just makes you look like a hobo. (3) Not shaving and showing up at a cocktail party makes you look like a hobo. (4) Taking a cold shower in a cold apartment makes me feel like a hobo that happened to catch a break and get into a luxurious bachelor pad.

Tuesday, September 05, 2006

Something I found...

OK. Here's something that should make you mad.


WHY ARE DRUGS SO EXPENSIVE? Answer: They're more expensive than you think.

If you asked someone on the street, they'd tell you it's because it takes pharmaceutical companies a long time--and a lot of money--to find a drug that treats a particular illness and is safe for use in humans. This is exactly the excuse pharmaceutical companies use too. When I started reading this article, I threw out a ballpark estimate percentage of the pharmaceutical research funding that was paid for by government dollars. I remember reading a few years ago in Parade magazine that 70% was PRIVATELY funded, so 30% came to mind right away. I said to myself, "maybe 50%." Then, not wanting to be overzealous, I backed off, coming to my final prediction of "25-50%".

I was way off.

OK, first of all think about what you pay in taxes. If the government says, "Because you spent this much on X thing, you don't have to pay taxes on that much of your income." That's a tax deduction. You pay tax on your income minus the amount you spent on X. That's NOT what pharmaceutical companies get. According to ?U.S.tax code, pharmaceutical companies get a tax CREDIT for their R&D expenditures. Thus, if they spend X dollars on R&D, at the end of the year they save X dollars in taxes. Now, pharmaceutical companies can claim tax credits for AT LEAST 50% of their R&D expenditures. This means that this tax rebate alone accounts for greater than or equal t0 50% of all the dollars spent on drug design studies, randomized clinical trials, etc. etc. Pharmaceutical companies are now paying for 50% or less of their "major" cost.

Second, the NIH. (NAtional Institutes of Health). The NIH funds well-designed studies that have anything remotely to do with physiology or medicine. Its budget is set by Congress and comes from the taxes that you and I pay. Research and development efforts undertaken by pharmaceutical companies are fundable by NIH dollars. Really fundable. ~10% of its annual budget fundable. The NIH budget fell off by ~$5 billion last year, but hopefully will rise to pre-2005 levels thanks to some good bipartisan legislation, back to ~$24 billion. So, each year that means that $2.4 billion IN ADDITION TO the tax credit finds its way from the federal government's coffers to the pockets of pharmaceutical companies.

So, the next time you're picking up the prescription at WalMart, look at the price tag. And add about 4 billion dollars. That's how much we're all really paying for drugs in the US.








--The source, for those who're interested...---
Within the medical/health industry, no sector receives better treatment under the tax code than the pharmaceutical industry. Federal tax credits include the Research and Experimentation Tax Credit, the Orphan Drug Tax Credit and the Possessions Tax Credit. A 1999 study conducted by the Congressional Research Service noted that between 1990 and 1996, just one tax credit alone saved drug companies $13 billion in federal taxes.23 A tax credit, which is a dollar-for-dollar reduction on taxes, is substantially more lucrative than a tax deduction. The Research and Experimentation Tax Credit allows a pharmaceutical company to reduce its tax obligation on a dollar-for-dollar basis by claiming a tax credit equal to at least 50 percent of the R&D expended by the company during the year.24 In other words, this tax credit alone publicly subsidizes 50 percent of all R&D research. Because of these tax credits, the pharmaceutical industry is the least taxed industry in the country.25 Families USA sums up the industry’s tax situation as follows:
Because research-related tax credits are reported along with other tax credits as “general business tax credits,” there are no publicly available data showing the exact amount of tax relief that the industry receives for its investment in research. However, the effect of tax credits is clear. In 1999, the Congressional Research Service (CRS) studied industry taxation for the years 1990 to 1996. CRS found that the drug industry was taxed relatively lightly; total tax credits, many related to research investments, lowered the industry’s effective tax rate from 35.2 percent to 17.1 percent. Given the favorable tax treatment of R&D, it is unlikely that the industry would turn to R&D first for spending reductions.26
Given the fact that the pharmaceutical industry is the most profitable industry in the country, it is ironic that its 16 percent tax rate is lower than that imposed on middle class Americans, who generally pay tax rates between 30 percent and 40 percent, or the average American business, which generally pays a federal tax of approximately 27 percent.27
In addition to tax credits, the pharmaceutical industry receives additional public tax dollars from federal medical organizations such as the National Institutes of Health (“NIH”). In 1950, the NIH had a total appropriation of $43 million.28 By 1998, the NIH received an appropriation of $13.6 billion.29 Congress subsequently committed to double the budget of the NIH between 1998 and 2003.30 By 2002, NIH’s budget was almost $24 billion.31 The majority of NIH funding -- pproximately 80 percent -- is awarded to research centers and universities; ten percent of NIH funding is used for research conducted by the NIH itself.32 At least one study of the 21 most important drugs introduced between 1965 and 1992 concluded that publicly funded research played a significant role in the development of 14 of the drugs.33 The NIH examined the top five selling drugs in 1995, each of which had over $1 billion in sales, and concluded that taxpayer funded researchers conducted 55 percent of the published research projects on these drugs.34 It also concluded that federal taxes also paid for approximately 30 percent of the published research of foreign academic institutions which participated in the development of these drugs.35

Monday, July 24, 2006

Entertaining, but not earth-shattering

M. Night Shymanaialainan has given us another Signs. That is, an MNS movie that you usually don't think about or particularly remember because of its mediocrity.

Lady in the Water was a satisfying enough movie, as was Signs. The characters were well contrived, humorous, archetypal, all that good stuff. The movie was entertaining, as well; Giamatti did perform excellently -- assuring us that he's going to be the next $50 million superstar. MNS portrayed one of the main characters, and it's at that point you realize why he's usually BEHIND the camera... because he sure as heck doesn't belong in front of it.

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Which brings me to what was WRONG with the movie -- and it's all in the writing. The basic principle of M. Night Shaymanyanmlan movies in the past has been that intervention by some supernatural force has changed the outcome of current events for the better. Even in Signs, the near-death ramblings of the preacher's wife allow humanity to defeat the alien menace. However, when watching LitW, you quickly realize that the only reason for the Lady's coming is... so that they can allow an eagle to come and take her away again? In her wake, she leaves nothing changed. Shaymamlalmyan's character (the writer) still publishes the book he was going to publish anyway, and we can assume that the future stays exactly the way it would have even if she hadn't come.

So, why the hell make a movie about a fairie coming to do nothing but cry and take showers? All good questions.

Well..., you ask me, what SHOULD have happened?

I had a great plan for the end of the movie, complete with an MNS-esque twist. Unfortunately, this movie was like Signs in that there was no twist at all. Of course, my version called for an evil Narf and the writer choosing to burn the manuscript after he finds out he'll be killed for it. After all, what's worth dying for? Some kid he'll never meet becoming president? That's awful self-sacrificing of the guy.

Thing is, I couldn't stand that at the end of the movie everyone was exactly the same as at the beginning. Nothing - changed. I guess maybe they had to get a new tenant for 13B. But that's about it.

--------------------


What I DID enjoy this weekend was getting my electricity back. Now I'm cleaning up and getting ready for my inspection tomorrow (what inspection? I don't know... they just posted something on my door today). I suppose just electrical wiring and stuff like that. Then I'm off for the library to get some more work done on this project -- we should have a manuscript done by the fall, which will be super sweet! Then next week I start Wash U Medical Plunge (WUMP) and will be busy shadowing public health officials, working in free clinics, doing the med student thing!! The week after is orientation, and then -- MED SCHOOL STARTS! I can't believe it's almost that time already.

Anyway, it's 11:30 and I'm already bushed. So I'll post more later. Take care everyone.

Friday, July 21, 2006

48 Hours

I'm just waiting for CBS to sue me for copyright violation. Let them try. I'll flee to Canada and live with the Canucks for a while.

Coming up on 48 hours with no electricity. In fact, in a shake-your-head-in-dismay-type twist, the short storm we had this morning took down ANOTHER power line next to my place. Because it fell into the street the intersection will be blocked off until the electric company gets around to fixing it.

Needless to say, I'm somewhat skeptical about getting electricity back anytime soon. The electric company was saying 72 hours, but if I'm watching DVDs by Monday or Tuesday I'll be happy.

So..................... until then................................. not too much .... to do....... Maybe write a ... uh... that novel I've been workin' on...... for, um, two years now............. make the main character a little bit more three-dimensional........ add in a little, um, a little personal experience............. Oh, I can't wait to read it.



I did have a brilliant recollection this afternoon - "Hey," I said to myself, "Lady in the Water premieres today." Of course, I've been looking forward to M. Night Shymaalailalaiynan's newest thriller for quite some time. Now, I know what you're all saying... "Two words, Boyum, The - Village." OK. The Village was worse than The Birds (see prior post for my feelings on that crapcake of a movie). But M. Night Shyyamayliyanalyian has had to live with that disgrace for two years. Now, he must realize that he has to make another GOOD movie like Unbreakable or The Sixth Sense to escape from it. And, come now, with a star like Paul Giamatti it's hard to go wrong.

As long as he plays a mopey guy, Giamatti is superb. I mean, it's hard to get more neurotic than Miles, his character in Sideways. Even in The Truman Show, in which his role called for more eating than speaking, he managed to portray the image that he was nothing but Ed Harris's bitch. So... I'll see how he does playing an average guy with no college buddies around played by Thomas Hayden Church. Should get interesting.

Picture 1: Mopey Giamatti in American Splendor,
Picture 2: Mopey Giamatti in The Truman Show,
Picture 3: Mopey Giamatti in Sideways...
















Man, thinking about Paul Giamatti in Truman Show made me hungry for some pizza. So, whup, see ya later.

Thursday, July 20, 2006

The Irony...

In perhaps the most ironic move in my recent life, yesterday about 4 hours before the storm, Netflix shipped me my first 3 DVD rentals. They arrived this afternoon.

1. Being John Malkovich
2. Syriana
3. The Game

When I got the email that they had been delivered, I said to myself, "Yes! I can't wait to watch them." Oh ... wait...

Well, I guess I'll enjoy them that much more when the power comes back on.

Power Outage

Well, no power expected for around 5 days, according to the newspaper this morning. 500,000 are without electricity today in St. Louis county. Worst storm to hit St. Louis in recent history, 80 mi/hr straight-line winds and all. Of course, this must be a resounding "WELCOME!" just for me. I'm like the Jonah of Missouri.

So I'm sticking around the hospital today (they have power, internet access, and AC, 3 things I don't). Later I have to go home and throw out 2 dozen eggs, half a gallon of milk, a 6 lb bag of chicken breasts and a box of 8 sirloin tip steaks. Dammit. :^(

BUT... I'm thankful. One high-rise downtown was taken down on top of Eads Bridge, trapping some people on the bridge during the storm. Some people were injured at the Cards game and had to be hospitalized. Long story short, it could have been much, much worse.

Disaster!

Thursday, June 29, 2006

Tomorrow, tomorrow, you're only a day away

Well, I'm taking a day off tomorrow to move into my new place. Ha haaa! I'm really excited - mostly to get out of this dump of a dorm. I don't mean that, it's a nice dorm, but people steal things like frying pans and spoonulas. Darn people.

My parents are bringing a load (and I mean, a FULL load) of crap down to me from home. I shouldn't say that, I'll hurt my best friend's feelings. The 'rents are staying in Wisconsin tonight and finishing the trip tomorrow morning, probably arriving sometime in the afternoon. We'll see, I guess. Then I have to take the various pieces of my bed from the truck, up three flights of stairs, into my new apartment. Then, assemble them into, you know, a bed. Should be fun. I hope to save the rest of my junk until my friend Nick gets back from a camping trip Sunday and has been nice enough to help me move some stuff in. Good ol' friends.

Of course, my parents are convinced that everything will be stolen out of the truck in the 48 hour interim.

But the streets of St. Louis seem to be a mite safer than the medical school dormitory in that regard.

Work is progressing - I actually collected my first data today. Further excitement. It's only a matter of time until the Nobel committee comes calling.















in memoriam - RIP spoonula